Steroids and derivatives
AdipoGen Ecdysterone
Chemical. CAS 5289-74-7. Formula C27H44O7. MW 480.63. Synthetic. A member of the ecdysteroid family. Ecdysone receptor EcR agonist. More potent than ecdysone. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs sites of high expression to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in moulting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins USP. Used for controlled gene expression in scientific research, agriculture and medicine. Used for the development of selective insect growth regulators for use as environmentally benign insecticides. Shows biological effects on mammalian species, including antiepileptic, antidiabetic, antiobesity, ROS-inhibiting activity.ht produces vitamin D3. UV/Vis lambdamax 271, 282, 293nm.
eMolecules Medchem Express / Guggulsterone / 5mg / 482203886 / HY-107738 / / 95975-55-6 / MFCD01310757 / 312.453 / C21H28O2
Medchem Express / Guggulsterone / 5mg / 482203886 / HY-107738 / / 95975-55-6 / MFCD01310757 / 312.453 / C21H28O2
AdipoGen Ecdysone
Chemical. CAS 3604-87-3. Formula C27H44O6. MW 464.6. Isolated from Ipomoea hederacea. Steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone. A member of the ecdysteroid family. Ecdysone receptor EcR agonist. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs sites of high expression to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in moulting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins USP. Appears in many plants mostly as a protection agent toxins or antifeedants against herbivorous insects. Used for controlled gene expression in scientific research, agriculture and medicine. Used for the development of selective insect growth regulators for use as environmentally benign insecticides.
Medchemexpress LLC Prostaglandin D2 | 41598-07-6 | MFCD00077857 | 99.5% | 352.47 g·mol⁻1 | C20H32O5 | 10 MG
Prostaglandin D2 is an endogenous prostaglandin provided as a synthetic, research-grade bioactive compound used to study PGD2-mediated signaling in neuroscience and inflammation research. It is suitable for in vitro and in vivo pharmacological assays where a defined, high-purity prostaglandin is required.
- High purity 99.5% suitable for research applications.
- Molecular formula C20H32O5 and molecular weight 352.47 g·mol⁻1.
- Available in small pack sizes for laboratory use (includes 10 mg).
- Used in pharmacology and neuroscience studies to investigate sleep and inflammatory signaling.
- Store under nitrogen at -80°C for long-term storage; short-term storage at -20°C.
U.S. Pharmacopeia Betamethasone | 378-44-9 | MFCD00062969 | 200mg
Betamethasone | 378-44-9 | MFCD00062969 | 200mg
Medchemexpress LLC Estrone O-sulfamate | 148672-09-7 | 100.0% | C18H23NO4S | 10MG
Estrone O-sulfamate is a research-grade steroid sulfatase inhibitor supplied as a high-purity solid for biochemical and pharmacological studies. It is intended for use in assays of steroid metabolism and enzyme inhibition, with recommended refrigerated storage and solvent stability guidelines for long-term experiments.
- Potent steroid sulfatase (STS) inhibitor suitable for in vitro studies.
- High purity solid for reliable analytical and biological assays.
- White to off-white powder, convenient for weighing and formulation.
- Stable under recommended storage conditions and protected from light.
- Available in small research pack sizes to minimize waste and enable pilot studies.
Medchemexpress LLC 7-methylguanosine-d3 | 00-00-0 | 98.5% | 301.29 g·mol⁻¹ | C11H13D3N5O5 | 5 MG
7-Methylguanosine-d3 is a deuterium-labeled stable isotope of 7-methylguanosine intended as a high-purity reference standard for analytical and biochemical applications. It is supplied in small-mass packages suitable for use in quantitative mass spectrometry, tracer studies, and method development. The unlabeled parent compound has reported activity against cNIIIB nucleotidase (IC50 = 87.8 ± 7.5 μM).
- High-purity deuterium-labeled isotopic standard for accurate mass spectrometry.
- Suitable as an internal standard for LC-MS or GC-MS quantitation.
- Useful for tracer studies and metabolic labeling experiments.
- Provided in small mass vials compatible with analytical workflows.
- Molecular formula C11H13D3N5O5; molecular weight 301.29 g·mol⁻¹.
Cayman Chemical 25-hydroxy VItamIn D2 500ug
A metabolite of vitamin D2; serum levels of 25-hydroxy vitamin D2 have been used as a marker of vitamin D status
Medchemexpress LLC HY-124619 5mg Medchemexpress, GPI-1046 CAS:186452-09-5 Purity:>98%
Medchemexpress, HY-124619 5mg GPI-1046 CAS:186452-09-5 GPI-1046 is a immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core. GPI-1046 is an analog of FK506, which is an immunophilin ligand that has been shown neuroprotective effects in neurodegenerative disease models. GPI-1046 readily crosses the blood-brain barrier and promotes the regeneration of dopamine (DA) cells in the CNS in association with functional recovery in rodent models. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.