Steroids and derivatives
Medchemexpress LLC Estrone sulfate potassium | 1240-04-6 | 99.9% | 388.52 | 1 MG
Estrone sulfate potassium | 1240-04-6 | 99.9% | 388.52 | 1 MG
Medchemexpress LLC Dopamine D2 receptor agonist-3 | 1257326-24-1 | 98.3% | 295.81 g/mol | C15H22ClN3O | 25 MG
Dopamine D2 receptor agonist-3 is a research compound characterized as a selective D2 receptor partial agonist and a D3 receptor antagonist. In vitro activity is reported with pEC50 8.3 at D2 and <5.5 at D3. In vivo, a 3 mg/kg (s.c.) dose demonstrated high brain penetration (brain:blood ratio ≈5.5) with Tmax ≈0.5 h. The compound is a solid with reported purity of 98.3% and molecular formula C15H22ClN3O.
- Selective D2 receptor partial agonist and D3 receptor antagonist.
- Reported pEC50 values: 8.3 (D2) and <5.5 (D3).
- High reported purity (98.3%).
- Solid form, suitable for research applications.
- Demonstrated brain penetration in vivo (3 mg/kg, s.c.; brain:blood ratio ~5.5).
- Available in small pack sizes, including 25 mg.
Medchemexpress LLC 2-Methylanisole-d3 | 258832-47-2 | ≥98.0% | 125.18 g·mol⁻¹ | C8H7D3O | 25 MG
2-Methylanisole-d3 is the deuterium-labeled analogue of 2-methylanisole supplied as a liquid isotopic reagent for synthetic chemistry and analytical applications. It is used as an internal standard in mass spectrometry and as a deuterated intermediate in the preparation of labeled compounds.
- Contains three deuterium atoms for isotopic labeling (molecular formula C8H7D3O).
- Molecular weight 125.18 g·mol⁻¹.
- Useful as an internal standard in mass spectrometry and quantitative analyses.
- Serves as a deuterated intermediate for synthesis of labeled compounds.
- Appearance: light brown to brown liquid; supplier documentation reports isotopic enrichment and chemical purity.
Cambridge Isotope Laboratories Acephate (methoxy-D3 thiomethoxy-D3 98%) 100 ug/mL in acetonitrile-D3 1 2 mL
Acephate (methoxy-D3 thiomethoxy-D3 98%) 100 ug/mL in acetonitrile-D3 1 2 mL
Cambridge Isotope Laboratories Hexamethylcyclotrisiloxane D3 (13C6 98%) 100 ug/mL in MTBE 1 2 mL
Hexamethylcyclotrisiloxane D3 (13C6 98%) 100 ug/mL in MTBE 1 2 mL
Medchemexpress LLC Impurity C of alfacalcidol | 82266-85-1 | MFCD22124488 | 99.8% | C35H49N3O4 | 10MG
Impurity C of alfacalcidol is an analytical reference impurity of the vitamin D analogue alfacalcidol, supplied as a high-purity solid for research use. It is intended for impurity profiling, analytical method development, and reference standard applications; follow recommended storage to preserve stability.
- High reported purity of 99.8%.
- Available in small solid quantities including 10 mg.
- Chemical formula C35H49N3O4; molecular weight 575.78.
- Suitable for impurity profiling and method development.
- Store protected from light and under inert atmosphere; in solvent keep at -80°C for long term.
Cambridge Isotope Laboratories 25-Hydroxyvitamin D3 (6 19 19-D3 97%) 1 mg
25-Hydroxyvitamin D3 (6 19 19-D3 97%) 1 mg
Medchemexpress LLC Fluorometholone (Standard) | 426-13-1 | 98.8% | 25 MG
Fluorometholone (Standard) is the analytical standard of Fluorometholone. This product is intended for research and analytical applications. Fluorometholone, a synthetic glucocorticoid, is a glucocorticoid receptor agonist with anti-inflammatory and anti-allergic properties. Fluorometholone can be used for the research of dry eye.
- The compound is the grade of analytical standard, which is the reference standard supplied assay.
- It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Medchemexpress LLC HY-N0554 5mg Medchemexpress, Escin IA CAS:123748-68-5 Purity:>98%
Medchemexpress, HY-N0554 5mg Escin IA CAS:123748-68-5 Escin IA is a triterpene saponin isolated from horse chestnut, which inhibits HIV-1 protease with IC50 values of 35 μM. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of epithelial-mesenchymal transition process by down-regulating LOXL2 expression. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Estrone sulfate (potassium) | 1240-04-6 | 99.9% | 388.52 | 25 MG
Estrone sulfate potassium is an inactive endogenous estrogen that can be converted into Estrone and Estradiol. It is also a substrate of the OATP1B3 transporter. This compound can be converted into Estrone and Estradiol in normal mammary parenchymal cells. It stimulates the growth of nitrosomethylurea-induced mammary tumors in ovariectomized rats and the colony formation of dispersed nitrosomethylurea mammary cells, with conversion occurring both in vivo and in vitro. This product is applicable to breast cancer-related research.
- An inactive endogenous estrogen
- Substrate of the OATP1B3 transporter
- Converted to estrone and estradiol in normal mammary parenchymal cells
- Stimulates growth of nitrosomethylurea-induced mammary tumors and colony formation of dispersed nitrosomethylurea mammary cells
- Applicable to breast cancer-related research
Cambridge Isotope Laboratories 25-Hydroxyvitamin D2 (unlabeled) 5 ug/mL in ethanol 1 mL
25-Hydroxyvitamin D2 (unlabeled) 5 ug/mL in ethanol 1 mL
Medchemexpress LLC Icariside D2 | 38954-02-8 | MFCD29059635 | 1 MG
Icariside D2 is a chemical compound isolated from the Annona glabra fruit. It is known for its ability to inhibit angiotensin-converting enzyme and exhibits a range of biological activities.
- Inhibits angiotensin-converting enzyme
- Shows cytotoxic activity on HL-60 cells with an IC50 value of 9.0 ± 1.0 μM
- Induces apoptosis
- Exhibits anti-inflammatory activity
- Exhibits anti-HIV activity